The Raelian Movement
for those who are not afraid of the future : http://www.rael.org
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~Life Extension Update
for those who are not afraid of the future : http://www.rael.org
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~Life Extension Update
Review explores effects of curcumin on lifespan
 |
Friday, January 25, 2013. A review published online on January 17, 2013 in the journal BioFactors documents a benefit for curcumin, a compound that occurs in the spice turmeric, in extending the life of several species. "The prospect that pharmaceutical and nutraceutical interventions may delay aging and age-related diseases is shared by many researchers," write Li-Rong Shen and his associates at the Jean Mayer-USDA Human Nutrition Research Center on Aging at Tufts University in their introduction. "By modulating putative biological processes of aging in mammalian cells and the entire body, specific foods can exert antioxidant activities, mitochondrial stabilization, metal chelating activities, inhibition of apoptosis of vital cells, and induction of cancer cell apoptosis. Thus, specific foods and herbs constitute a great promise to improve health and prevent age-related chronic diseases."
The authors discuss experimental investigations of the effects of curcumin or the curcumin metabolite tetrahydrocurcumin (THC) on life span. In a study involving the roundworm C. elegans, growth media containing a low concentration of curcumin increased mean (average) lifespan by 39 percent and maximum lifespan by 21.4 percent. (Maximum lifespan refers to the maximum number of days or years that a species is believed to be capable of surviving. The maximum lifespan of humans is currently agreed upon as 122 years.) The researchers also documented a reduction in reactive oxygen species, decreased lipofuscin levels (indicating less cellular damage during aging) and greater resistance to heat stress in curcumin-treated worms in comparison with untreated controls.
In a study with fruit flies, which generally survive an average of 64 days, an increase of mean lifespan to 80 days occurred in curcumin-fed flies. Another study involving two strains of flies found varying effects of curcumin in male and female flies, with females of one strain and males of another strain experiencing an extension in lifespan. A third fly study also revealed a variation in male and female response to curcumin, although the compound was shown to extend life in both genders.
The curcumin metabolite tetrahydrocurcumin has also been associated with lifespan extension. In male mice supplemented with THC beginning at the age of 13 months, mean lifespan was increased by an average of 84 days in comparison with unsupplemented mice. Tetrahydrocurcumin was also shown to extend lifespan and reduce oxidative stress in male and female fruit flies; however, research findings from this study suggest that the mechanism involved in lifespan extension may not be related to curcumin's antioxidant activity.
"Given the long and established history of turmeric as a spice and herbal medicine, its demonstrated chemopreventive and therapeutic potential, and its pharmacological safety in model systems, curcumin, the bioactive extract of turmeric, promises a great future in human clinical studies designed to prevent and/or delay age-related diseases," the authors conclude. "Extensive, well-controlled clinical trials are now needed to evaluate fully the potential of curcumin in terms of optimal dose, route of administration, and potential interactions with other drugs."
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
WARNING FROM RAEL: For those who don't use their intelligence at its
full capacity, the label "selected by RAEL" on some articles does not
mean that I agree with their content or support it. "Selected by RAEL"
means that I believe it is important for the people of this planet to
know about what people think or do, even when what they think or do is
completely stupid and against our philosophy. When I selected articles
in the past about stupid Christian fundamentalists in America praying
for rain, I am sure no Rael-Science reader was stupid enough to believe
that I was supporting praying to change the weather. So, when I select
articles which are in favor of drugs, anti-Semitic, anti-Jewish, racist,
revisionist, or inciting hatred against any group or religion, or any
other stupid article, it does not mean that I support them. It just
means that it is important for all human beings to know about them.
Common sense, which is usually very good among our readers, is good
enough to understand that. When, like in the recent articles on drug
decriminalization, it is necessary to make it clearer, I add a comment,
which in this case was very clear: I support decriminalizing all drugs,
as it is stupid to throw depressed and sad people (as only depressed and
sad people use drugs) in prison and ruin their life with a criminal
record. That does not mean that there is any change to the Message which
says clearly that we must not use any drug except for medical purposes.
The same applies to the freedom of expression which must be absolute.
That does not mean again of course that I agree with anti-Jews,
anti-Semites, racists of any kind or anti-Raelians. But by knowing your
enemies or the enemies of your values, you are better equipped to fight
them. With love and respect of course, and with the wonderful sentence
of the French philosopher Voltaire in mind: "I disapprove of what you
say, but I will defend to the death your right to say it".
WARNING FROM RAEL: For those who don't use their intelligence at its
full capacity, the label "selected by RAEL" on some articles does not
mean that I agree with their content or support it. "Selected by RAEL"
means that I believe it is important for the people of this planet to
know about what people think or do, even when what they think or do is
completely stupid and against our philosophy. When I selected articles
in the past about stupid Christian fundamentalists in America praying
for rain, I am sure no Rael-Science reader was stupid enough to believe
that I was supporting praying to change the weather. So, when I select
articles which are in favor of drugs, anti-Semitic, anti-Jewish, racist,
revisionist, or inciting hatred against any group or religion, or any
other stupid article, it does not mean that I support them. It just
means that it is important for all human beings to know about them.
Common sense, which is usually very good among our readers, is good
enough to understand that. When, like in the recent articles on drug
decriminalization, it is necessary to make it clearer, I add a comment,
which in this case was very clear: I support decriminalizing all drugs,
as it is stupid to throw depressed and sad people (as only depressed and
sad people use drugs) in prison and ruin their life with a criminal
record. That does not mean that there is any change to the Message which
says clearly that we must not use any drug except for medical purposes.
The same applies to the freedom of expression which must be absolute.
That does not mean again of course that I agree with anti-Jews,
anti-Semites, racists of any kind or anti-Raelians. But by knowing your
enemies or the enemies of your values, you are better equipped to fight
them. With love and respect of course, and with the wonderful sentence
of the French philosopher Voltaire in mind: "I disapprove of what you
say, but I will defend to the death your right to say it".
--
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
There is nothing glorious about what our ancestors call history,
it is simply a succession of mistakes, intolerances and violations.
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
Rael
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Tell your friends that they can subscribe to this list by sending an email to:
subscribe@rael-science.org
- - -
To unsubscribe, send an email to:
unsubscribe@rael-science.org
- - -
ไม่มีความคิดเห็น:
แสดงความคิดเห็น