วันพฤหัสบดีที่ 28 กุมภาพันธ์ พ.ศ. 2556

[rael-science] Something fishy on your plate: Study finds rampant mislabelling of seafood sold in U.S.‏


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The Raelian Movement
for those who are not afraid of the future : http://www.rael.org   
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Contributed by Dominic Lejeune
Source: http://www.cbsnews.com/8301-201_162-57570489/something-fishy-on-your-plate-study-finds-rampant-mislabeling-of-seafood-sold-in-u.s/

Something fishy on your plate: Study finds rampant mislabelling of seafood sold in U.S.

In this 2008 photo released by the South Atlantic Fishery Management Council, red snapper, foreground, caught by commercial fishermen in the fall of 2008 is boxed at a dock in Mount Pleasant, S.C., before being taken to market to be sold to restaurants.
In this 2008 photo released by the South Atlantic Fishery Management Council, red snapper, foreground, caught by commercial fishermen in the fall of 2008 is boxed at a dock in Mount Pleasant, S.C., before being taken to market to be sold to restaurants. / AP Photo/South Atlantic Fishery Management Council
A third of the seafood sold in the United States is mislabeled and consumers don't have a clue, new research has found.
According to the conservation organization Oceana, fish sold as snapper has the highest mislabeling rate. The group's the study shows that 87 percent of the time you think you're buying snapper, you're actually being given something else.
Tuna was next on the list as 59 percent of the samples were identified by DNA analysis as something other than what was on the label. Oceana claims its study is one of the largest seafood fraud investigations in the world to date.
Oceana analyzed 1,215 seafood samples from 674 retail outlets in 21 states between 2010 and 2012. The group's research was restricted to retail outlets including restaurants, sushi outlets and grocery stores. The group did not identify individual outlets as it could not say exactly where in the supply chain the seafood fraud occurred.
Play Video

Headlines: One-third of seafood sold mislabeled

The group called for a comprehensive and transparent traceability system - one that tracks fish from boat to plate - to be established at the national level. It also demanded increased inspection and testing of U.S. seafood, specifically for mislabeling, and stronger federal and state enforcement of existing laws combating fraud.
"Our government has a responsibility to provide more information about the fish sold in the U.S., as seafood fraud harms not only consumers' wallets, but also every honest vendor and fisherman cheated in the process;to say nothing of the health of our oceans," the group said.
-- 
-- 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
 
There is nothing glorious about what our ancestors call history, 
it is simply a succession of mistakes, intolerances and violations.
 
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
 
Rael
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
Tell your friends that they can subscribe to this list by sending an email to:
subscribe@rael-science.org
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[rael-science] Sugata Mitra: Build a School in the Cloud‏


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
The Raelian Movement
for those who are not afraid of the future : http://www.rael.org   
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Source: http://www.ted.com/talks/sugata_mitra_build_a_school_in_the_cloud.html

Sugata Mitra: Build a School in the Cloud

22:31 minutes · Filmed Feb 2013 · Posted Feb 2013 · TED2013
Onstage at TED2013, Sugata Mitra makes his bold TED Prize wish: Help me design the School in the Cloud, a learning lab in India, where children can explore and learn from each other -- using resources and mentoring from the cloud. Hear his inspiring vision for Self Organized Learning Environments (SOLE), and learn more at tedprize.org.
Educational researcher Sugata Mitra is the winner of the 2013 TED Prize. His wish: Build a School in the Cloud, where children can explore and learn from one another.
Watch now »


-- 
-- 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
 
There is nothing glorious about what our ancestors call history, 
it is simply a succession of mistakes, intolerances and violations.
 
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
 
Rael
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
Tell your friends that they can subscribe to this list by sending an email to:
subscribe@rael-science.org
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To unsubscribe, send an email to:
unsubscribe@rael-science.org
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[rael-science] Why It Is Ethical to Cure the Disease of Aging‏


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
The Raelian Movement
for those who are not afraid of the future : http://www.rael.org   
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Source: http://mariakonovalenko.wordpress.com/2013/02/27/why-it-is-ethical-to-cure-the-disease-of-aging/

February 27, 2013 

Why It Is Ethical to Cure the Disease of Aging

Arthur Caplan, renowned bioethicist, presents simply brilliant argumentation that aging is an unnatural process in this paper. It’s a must-read. I’d love to highlight the main thoughts that I find are profoundly important for the whole fighting aging field.
Why do the doctors treat atherosclerosis and cancer, but not the physiological changes and deteriorations, associated with aging?
Progeria—rapid ageing in a child—is considered a horrible disease, whereas the same changes occurring 80 years later are considered normal and unworthy of medical interest.
The reason is because aging is not being thought of as a disease by doctors and the rest of the world. But it should be!
… in medical dictionaries, disease is almost always defined as any pathological change in the body. Pathological change is inevitably defined as constituting any morbid process in the body… ageing would there- fore seem to have a prima facie claim to being counted as a disease.
One thing that does differentiate ageing from other processes or states traditionally classified as disease is the fact that ageing is perceived as a natural or normal process.
So, the main thesis of the article is that aging is an unnatural process. Dr. Caplan says that if that were not true, then there must have been compelling evidence that aging is natural “and, as such, intrinsically good thing.” This brings us to figuring out what is believed to be natural in medicine. Well, it turns out, one view is that it’s common and normal process that affects 100% of the population.
Coronary atherosclerosis, neoplasms, high blood pressure, sore throats, colds, tooth decay and depression are all nearly universal in their distribution and seem to be inevitable phenomena, yet we would hardly call any of these things natural. The inevitability of infectious disease does not cause the physician to dismiss infections as natural occurrences of no particular medical interest.
The other point of view on what is natural and what’s not comes from considering purpose and function. In order to decide whether aging is natural or not, we should define its function. There are two explanations. The first one is religious, where the vindictive god wants the people to remember they are morally weak. As Dr. Caplan notes, this can’t be used as a scientific explanation, which leaves us with the second point of view “that the purpose or function of ageing is to clear away the old to make way for the new.” Evolutionary biologists tried to explain what aging is and why it is needed based on the concept of natural selection.
More surprisingly, the scientific explanation of ageing as serving an evolutionary role is also not true, because it rests on a faulty evolutionary analysis.
Given that selective forces act on individuals and their genotypes and not species, it makes no sense to speak of ageing as serving an evolutionary function or purpose to benefit the species.
I find this thought genius. It seems to me so obvious now when I’ve read it. Indeed, this has always been overlooked by aging biologists. Evolutionary theories have always seemed so dangerously appealing that it might have drawn aging biologists (like Tom Kirkwood, for example) away from fighting aging. A lot of scientists still think aging is natural and I believe the evolutionary theories have played a major role in forming this belief. This may be the underlying reason why researchers can’t accept the thought that aging can and should be cured. Dr. Caplan defines aging in the following way:
Ageing exists, then, as a consequence of a lack of evolutionary foresight; it is simply a by-product of selective forces that work to increase the chances of reproductive suc- cess. Senescence has no function; it is simply the inadvertent subversion of organic func- tion, later in life, in favour of maximizing reproductive advantage early in life.
The common belief that ageing serves a function or purpose, if this belief is based on a misapprehension of evolutionary theory, is mistaken. And, if this is so, it would seem that the common belief that ageing is a natural process is also mistaken. And if that is true, and if it is actually the case that what occurs during the ageing process parallels the changes that occur during paradigmatic examples of disease (Boorse, 1975), then it would be reasonable to consider ageing as a disease.
The explanation of why ageing occurs has many of the attributes of a stochastic or chance phenomenon. And this makes ageing unnatural and in no way an intrinsic part of human nature. As such, there is no reason why it is intrinsically wrong to try to reverse or cure ageing.
There is no reason why we can’t call aging a disease. There is no ethical reason why we shouldn’t try to slow down or reverse aging. There is no ethical reason why we shouldn’t fight aging – the worst disease of all times.
-- 
-- 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
 
There is nothing glorious about what our ancestors call history, 
it is simply a succession of mistakes, intolerances and violations.
 
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
 
Rael
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
Tell your friends that they can subscribe to this list by sending an email to:
subscribe@rael-science.org
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[rael-science] Stretchy battery drawn to three times its size‏

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The Raelian Movement
for those who are not afraid of the future : http://www.rael.org   
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Contributed by Mike Bennett
Source: http://www.bbc.co.uk/news/science-environment-21585817

26 February 2013

Stretchy battery drawn to three times its size

Battery
        stretched by 300% The team tested their battery by stretching it 300% while it powered an LED lamp
Researchers have demonstrated a flat, "stretchy" battery that can be pulled to three times its size without a loss in performance.
While flexible and stretchable electronics have been on the rise, powering them with equally stretchy energy sources has been problematic.
The new idea in Nature Communications uses small "islands" of energy-storing materials dotted on a stretchy polymer.
The study also suggests the batteries can be recharged wirelessly.
In a sense, the battery is a latecomer to the push toward flexible, stretchable electronics. A number of applications have been envisioned for flexible devices, from implantable health monitors to roll-up displays.
But consumer products that fit the bendy, stretchy description are still very few - in part, because there have been no equally stretchy, rechargeable power sources for them.
"Batteries are particularly challenging because, unlike electronics, it's difficult to scale down their dimensions without significantly reducing performance," said senior author of the study John Rogers of the University of Illinois at Urbana-Champaign.
S for stretch
"We have explored various methods, ranging from radio frequency energy harvesting to solar power," he told BBC News.
In recent years, Prof Rogers worked with colleagues at Northwestern University, focusing on stretchy electronics of various sorts made using what they termed a "pop-up" architecture. The idea uses tiny, widely spaced tiny circuit elements embedded within a stretchy polymer and connected with wires that "popped up" as the polymer was stretched.
Microscope
          image of battery elements and serpentine connections The new work hinges on "self-similar", serpentine wires between the battery elements
But batteries do not lend themselves to this idea; traditionally they are much larger than other circuit elements. They could be made from smaller elements wired together, but to create a small battery with sufficient power, the elements must be spaced more closely than those of the pop-up circuits.
The team's new idea was to use "serpentine" connections - wires that loop back on themselves in a repeating S shape, with that string of loops itself looped into an S shape.
Stretching out the polymer in which the tiny solar cells were embedded first stretches out the larger S; as it is stretched further, the smaller turns straighten - but do not become taut, even as the polymer was stretched to three times its normal size.
The team says the stretchy battery can be charged "inductively" - that is, wirelessly over a short distance. Prof Rogers said that the uses for such batteries and the stretchy circuits they power were myriad.
"The most important applications will be those that involve devices integrated with the outside of the body, on the skin, for health, wellness and performance monitoring," he explained.
However, the prototype batteries described in the paper were only run through 20 charge/discharge cycles, and Prof Rogers said that "additional development efforts to improve the lifetime will be required for commercialisation".


-- 
-- 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
 
There is nothing glorious about what our ancestors call history, 
it is simply a succession of mistakes, intolerances and violations.
 
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
 
Rael
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
Tell your friends that they can subscribe to this list by sending an email to:
subscribe@rael-science.org
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[rael-science] Innovating Our Way To A Peaceful and Liberating Anarchy‏

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
The Raelian Movement
for those who are not afraid of the future : http://www.rael.org   
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Source: http://www.radicalabundance.org/innovating-our-way-to-a-peaceful-and-liberating-anarchy/

Innovating Our Way To A Peaceful and Liberating Anarchy

By Paul Hughes
Below is a visionary and concrete proposal on how humanity can create a truly free and peaceful society without coercion of any kind. A decentralized, networked society of rising collective intelligence that transcends any need for laws, legal codes, lawyers, police, courts, prisons or military force. It presents the idea of how laws are not only becoming unenforceable  but eventually unnecessary given sufficient forkability, transparency and material abundance. There are others who have talked about similar ideas like polycentric law, Jordan Greenhall’s ‘liquid jurisprudence, and Roderick Long’s  post-punitive restitution system.
So how do we get there?
Below are three trends that could radically transform our society from one ruled by law or force to one that is free of all such constraints, while maximizing freedom and peaceful coexistence for all human beings. It won’t happen overnight, or all at once, but in fits and spurts as people adjust to the new structural reality.
  1. Radical Transparency. Everything is inexorably becoming more transparent. Nobody, not even governments or other secret organizations, are immune. What we are witnessing today is an ongoing explosion of open and uncensorable information, and a radical democratization of intelligence where no one has the surveillance advantage. The tools of sousveillance are moving towards ubiquity – a sort of adhoc Wiki Intelligence Agency (WIA) where everyone has access. But it’s not centralized in any way, it is simply the open network itself. The tools of ubiquitous recording devices, nearly unlimited public/cloud storage, inability to contain leaks, and equal access to sun-mass computation encryption, will utterly level the playing field when it comes to the “intelligence” game. This transformation is already in full swing - Mega, cell phone cameras, DIY drones, YouTube, Anonymous, Wikileaks, etc. David Brin pioneered this idea in his 1989 book, The Transparent Society. Most importantly of all, is that open information networks simply out-compete secret ones, because secrecy breeds suspicion, closed channels and subsequently, stupidity. Open is simply smarter than secret.
  2. Ubiquitous Reputation Metrics. Functionally speaking, this is the same thing as radical transparency. Examples, albeit primitive, of how reputation works is in places like Amazon and Ebay. When you do business with another individual on Ebay, you can decide who to do business with based on their reputation. All things being equal, the rational choice is to interact with the person who has the highest reputation. But imagine instead that you have the tools yourself, with far more dimensionality and granularity, for maximizing harmonization and trusting relationships with others based on your own definitions of what that is. No one controls or mediates this reputation. It will be completely disintermediated. You are making your own judgement based on the information that is available on the open/transparent network. Daniel Suarez in his book Freedom, the highly engaging sequel to Daemon, describes a type of society like this that could emerge in the medium term. What is interesting here is that Radical Transparency automatically equals Ubiquitous Reputation. For all intents and purposes they are the same thing.
  3. Radical Abundance. This is a big one, save it to say that the technologies for uplifting the rest of humanity out of poverty are coming. There will be no basic want, and in fact it can be argued, that most everyone will have access to the highest technologies available at next to zero cost from abundant cheap solar energy, mature 3d printing from recycled materials, and a gargantuan library of 3d downloadable designs. Why steal when you can download and print whatever you need for free? The truth is that almost all crime and criminality comes from a place of scarcity. Eliminate scarcity and you eliminate most of the source causes of crime in the first place. But lets address the what if’s of how society might overcome bad actors and actions.

Stigmergic Society – Spontaneous Order without Orderers

The best way to think of a how a highly peaceful and harmonious society could emerge without a legal code is the concept of Stigmergy. A school of fish is a good example. Each fish is acting in their own best interest and yet they spontaneously collaborate - creating a collectively intelligent order without orderers, an evolutionary adaptation that serves them well! When you try to punch or harm a school of fish, the school forms a hole immediately where your hand went, allowing the fish to escape your grasp. This is how networks route around damage. Networks allow human beings to do the same thing! Stigmergic cooperation enables networked humans to peacefully out-smart and out-maneuver predators and tyrants at every turn. Those who continue to act badly towards others will simply be wasting their energy punching holes in “schools of fish”. The worse a person’s reputation is the more transparent and obvious that will be to others and the easier it will be to out-maneuver them. There is no inherent negativity. Think of it as highly nimble social aikido.
Based on my analysis the longer this plays out, those who are unethical, corrupt, predatory, will have nowhere to hide. See The New Political Asymmetry. Bad actors will be seen as damage by the network, and routed around, just like censorship is. There is this idea that somehow criminals will be able to mount some kind of conspiracy, but how would such a conspiracy ever get past the planning stages, when it becomes impossible to hide their actions, especially when the people involved most likely have bad reputations, and thus more stigmergic eyes watching them? This isn’t oppressive, this is just stigmergic out-maneuvering. Stigmergic society won’t stop predators from being predators, that’s their prerogative. They will simply be irrelevant in the face of a more adaptive collectively intelligent human network. And that is exactly what p2p networks do – render bad actors and actions irrelevant. This is a fact of network life, of uncensorable information channels. Don’t believe me? Look at how thoroughly the music industry has failed to stop music sharing, or organizations keeping secrets, once those secrets are out on the internet.
Bad actors will be left with few choices, other than to better themselves for want of anything else. They can play nice and cooperate, form their own more isolated collectives, or be alone. The choice and freedom is theirs to make. They will have the same tools of abundance as everyone else, so there will be less reason for them to steal in the first place, and more opportunities to become better people through a growing open-source repository of self-improvement and mental health services and technologies.
What I think makes this hard for people to grasp, is right now there are so many pathways for intelligent sociopaths to make headway. Robert Shea referred to this as The Empire of The Rising ScumKevin Carson talks about it too. Fortunately this only remains true as long as you have hierarchical/centralized points of failure, in which co-opting it actually gives you some kind of advantage. But in a p2p world of radical abundance, such advantages simply won’t exist. And to whatever degree they do, radical transparency makes it difficult, if not impossible for anyone without sufficiently high reputations to have any meaningful influence.

A Beautiful and Peaceful Anarchy?

So what about laws? Don’t people need rules in which they must obey in order for society to function properly? As can be seen above, the answer is looking increasingly like ‘no’. Mutual/consensual agreements, principles that emerge naturally and spontaneously, yes. Fluid agreements that everyone has full power over whether to participate in, change, revoke or fork. People who have similar ideas on how things should work will have higher matched metrics of compatibility and will contract with each other. The current lack of transparency, mobility and forkability is the reason there are so many otherwise incompatible people living on top of each other. Because of the nature of unique reputation metrics for each person, people will no longer be trapped within one tribe or community, but free to explore, grow and expand outwards into increasingly coherent networks of kindred spirits. Because of that level of mobility, permeability and coherency, human conflict will be reduced significantly. Radical forking will allow for a vast diversity of ever changing, participatory, evolutionary, revocable, consensual agreements/rule-sets.  Reputation will be the new currency. It will be your unique self, and help you find the most compatible connections with others.

Crimes of Passion?

My wife had mentioned to me that crimes of passion could slip through the cracks of the above decentralized system. She used the example of a drunk driver running over and killing another man’s daughter outside his house. In a fit of rage the father kills the drunk driver. So how could an open-sourced decentralized society solve this particular problem?
Well the honest truth is it sometimes takes tragedies like this for people to develop the necessary work-arounds. The brilliant part of an open-source peer produced society is it would respond *very* quickly with innovative solutions. Those solutions, regardless of where they were developed, would quickly spread throughout a network, and be adopted wherever they would be appropriate. Mark Pesce calls this ‘hypernomadism’. So lets see how this would resolve the above drunk driving problem.
They are already working on open-source cars. Not only are people working on open-source cars, but cars that can drive themselves. Google has been given permission here in Nevada to begin test driving them. As those vehicles become available, the market and public pressure will steer the open-source community to include the “auto-drive” feature as a basic feature in cars going forward. Those people who don’t include that feature will have their reputation reduced and go out of business unless they include this new feature. Bartenders who allow their patrons to arrive without safe transportation home will also receive bad reputations scores once the bad publicity goes viral. Bartenders will quickly respond by making sure their patrons get home safe. Compare this solution to the current effectiveness of drunk driving laws. The solution above will do far far more to reduce it than any law ever could. Those bartenders who, because of their own negligence, did not make sure their patrons got home safe, when the open-source market makes it easy for them to do so, will go out of business.
My point is that if there is a solution, anywhere, allowed by the laws of physics, an open-source peer produced society will solve these problems far faster, better and more harmoniously without oppression, than any law ever could.

Addendum: Making Intoxicated Driving Safe and Fun

Here’s an interesting twist on the auto-drive feature. Given sufficient on-board intelligence, the drunk driver could actually go on a joy ride, with him steering the wheel, with the on-board IQ augmenting, and correcting when necessary any unsafe movements. It could be so seamless, that the drunk driver feels like he himself is driving, and going where he wants to go, but all the while, the car is behaving safer than the most expert sober driver ever could. This seamlessness would be achieved by actuators that auto-correct over 1000 times per second. Such technology already exists, and is used in airplanes like the F-22.


-- 
-- 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
 
There is nothing glorious about what our ancestors call history, 
it is simply a succession of mistakes, intolerances and violations.
 
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
 
Rael
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
Tell your friends that they can subscribe to this list by sending an email to:
subscribe@rael-science.org
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[rael-science] Bad sleep 'dramatically' alters body‏

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
The Raelian Movement
for those who are not afraid of the future : http://www.rael.org   
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Contributed by Mike Bennet
Source: http://www.bbc.co.uk/news/health-21572686

25 February 2013

Bad sleep 'dramatically' alters body

A run of poor sleep can have a potentially profound effect on the internal workings of the human body, say UK researchers.
The activity of hundreds of genes was altered when people's sleep was cut to less than six hours a day for a week.
Writing in the journal PNAS, the researchers said the results helped explain how poor sleep damaged health.
Heart disease, diabetes, obesity and poor brain function have all been linked to substandard sleep.
What missing hours in bed actually does to alter health, however, is unknown.
So researchers at the University of Surrey analysed the blood of 26 people after they had had plenty of sleep, up to 10 hours each night for a week, and compared the results with samples after a week of fewer than six hours a night.
More than 700 genes were altered by the shift. Each contains the instructions for building a protein, so those that became more active produced more proteins - changing the chemistry of the body.
Meanwhile the natural body clock was disturbed - some genes naturally wax and wane in activity through the day, but this effect was dulled by sleep deprivation.
Prof Colin Smith, from the University of Surrey, told the BBC: "There was quite a dramatic change in activity in many different kinds of genes."
Areas such as the immune system and how the body responds to damage and stress were affected.
Prof Smith added: "Clearly sleep is critical to rebuilding the body and maintaining a functional state, all kinds of damage appear to occur - hinting at what may lead to ill health.
"If we can't actually replenish and replace new cells, then that's going to lead to degenerative diseases."
He said many people may be even more sleep deprived in their daily lives than those in the study - suggesting these changes may be common.
Dr Akhilesh Reddy, a specialist in the body clock at the University of Cambridge, said the study was "interesting".
He said the key findings were the effects on inflammation and the immune system as it was possible to see a link between those effects and health problems such as diabetes.
The findings also tie into research attempting to do away with sleep, such as by finding a drug that could eliminate the effects of sleep deprivation.
Dr Reddy said: "We don't know what the switch is that causes all these changes, but theoretically if you could switch it on or off, you might be able to get away without sleep.
"But my feeling is that sleep is fundamentally important to regenerating all cells."



-- 
-- 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
 
There is nothing glorious about what our ancestors call history, 
it is simply a succession of mistakes, intolerances and violations.
 
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
 
Rael
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
Tell your friends that they can subscribe to this list by sending an email to:
subscribe@rael-science.org
- - -

[rael-science] BPA May Affect the Developing Brain by Disrupting Gene Regulation‏


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
The Raelian Movement
for those who are not afraid of the future : http://www.rael.org   
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Source: http://www.alnmag.com/news/bpa-may-affect-developing-brain-disrupting-gene-regulation

BPA May Affect the Developing Brain by Disrupting Gene Regulation

News Posted: February 26, 2013


Duke Univ.
Exposure to BPA may disrupt development of the central nervous system by slowing down the removal of chloride from neurons. As an organism matures and the brain develops, chloride levels inside nerve cells drop. However, when exposed to BPA, the chloride is removed more slowly from neurons. Researchers also found female neurons to be more susceptible to the effects of BPA.Courtesy of Duke Univ.
Environmental exposure to bisphenol A (BPA), a widespread chemical found in plastics and resins, may suppress a gene vital to nerve cell function and to the development of the central nervous system, according to a study led by researchers at Duke Medicine.
The researchers published their findings — which were observed in cortical neurons of mice, rats and humans — in the journal Proceedings of the National Academy of Sciences.
"Our study found that BPA may impair the development of the central nervous system, and raises the question as to whether exposure could predispose animals and humans to neurodevelopmental disorders," says lead author Wolfgang Liedtke, associate professor of medicine/neurology and neurobiology at Duke.
BPA, a molecule that mimics estrogen and interferes with the body's endocrine system, can be found in a wide variety of manufactured products, including thermal printer paper, some plastic water bottles and the lining of metal cans. The chemical can be ingested if it seeps into the contents of food and beverage containers.
Research in animals has raised concerns that exposure to BPA may cause health problems such as behavioral issues, endocrine and reproductive disorders, obesity, cancer and immune system disorders. Some studies suggest that infants and young children may be the most vulnerable to the effects of BPA, which led the U.S. Food and Drug Administration to ban the use of the chemical in baby bottles and cups in July 2012.
While BPA has been shown to affect the developing nervous system, little is understood as to how this occurs. The research team developed a series of experiments in rodent and human nerve cells to learn how BPA induces changes that disrupt gene regulation.
During early development of neurons, high levels of chloride are present in the cells. These levels drop as neurons mature, thanks to a chloride transporter protein called KCC2, which churns chloride ions out of the cells. If the level of chloride within neurons remains elevated, it can damage neural circuits and compromise a developing nerve cell's ability to migrate to its proper position in the brain.
Exposing neurons to minute amounts of BPA alters the chloride levels inside the cells by somehow shutting down the Kcc2 gene, which makes the KCC2 protein, thereby delaying the removal of chloride from neurons.
MECP2, another protein important for normal brain function, was found to be a possible culprit behind this change. When exposed to BPA, MECP2 is more abundant and binds to the Kcc2 gene at a higher rate, which might help to shut it down. This could contribute to problems in the developing brain due to a delay in chloride being removed.
These findings raise the question of whether BPA could contribute to neurodevelopmental disorders such as Rett syndrome, a severe autism spectrum disorder that is only found in girls and is characterized by mutations in the gene that produces MECP2.
While both male and female neurons were affected by BPA in the studies, female neurons were more susceptible to the chemical's toxicity. Further research will dig deeper into the sex-specific effects of BPA exposure and whether certain sex hormone receptors are involved in BPA's effect on KCC2.
"Our findings improve our understanding of how environmental exposure to BPA can affect the regulation of the Kcc2 gene. However, we expect future studies to focus on what targets aside from Kcc2 are affected by BPA," Liedtke says. "This is a chapter in an ongoing story."
Source: Duke Univ.
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"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
 
There is nothing glorious about what our ancestors call history, 
it is simply a succession of mistakes, intolerances and violations.
 
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
 
Rael
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